These pains often are migratory in nature, that is, in turn, Different joints hurt, but symmetrical (meaning «together» sore knee joints or joints on certain fingers or toes). Then start complaints of morning stiffness in his movements, and similar symptoms at night, as well as pain, aggravated by movement.When the main symptoms of arthritis — pain and limitation of joint mobility (especially multiple joints) — should, without delay, consult your doctor.The third stage of the inflamed cells release the enzyme that affects bone and cartilage that commonly leads to deformation of the joint, pain and restriction of the increase of motor function. Typically, the disease progresses slowly at first, with the gradual deployment of clinical symptoms for months or years, much less acute.
About two-thirds of cases occur arthritis, ie the defeat of several joints. The more joints affected, the more advanced stages of the disease.
Rheumatoid arthritis is often associated with other diseases of the joints — osteoarthritis, rheumatism, systemic connective tissue diseases.
In addition to joint pain and mobility limitation, rheumatoid arthritis patients may complain of fever, weakness, weight loss, loss of appetite, depression, muscle pain, increased sweating.
For a long time there was no method to establish that this type of arthritis is rheumatoid. Currently, diagnosis of this disease is based, in addition to clinical symptoms, blood for biochemical analysis and X-ray joints.
In the biochemical analysis of blood examined SEC, rheumatoid factor, etc. The most progressive and reliable analysis is an indicator of the amount of antibodies to cyclic tsitrulinovomu peptide (anti-CCP).